Principal Investigator

Dr. Cristina Risco is a group leader and head of the Cell Structure Laboratory at the National Center for Biotechnology, one of the institutes of the National Research Council of Spain. She obtained her PhD in biology from the Complutense University of Madrid, conducted postdoctoral research at the National Cancer Institute (NCI-FCRDC, NIH, MD, USA) and worked as a visiting scientist at the Max Plank Institute for Biochemistry (Martinsried, Germany), the Université Pierre et Marie Curie and the Institut Jacques Monod (Paris, France).

Present work

Dr. Risco’s research makes use of current developments in imaging technology to study virus-host interactions.rg





Martin Sachse obtained his PhD in 2003 at the Univerity of Utrecht (The Netherlands) and worked for more than fifteen years in one of the two EM facilities (Utechs Ubi) of the Institut Pasteur, Paris (France). In 2021, he joined the CSL during his sabbat year to work as a visitor scientist on the imaging of viral infections with different EM methods.

Present work

Martin currently works at the Instituto de Salud Carlos III, Madrid, and collaborates with the CSL to study the mechanism of action of antiviral drugs using EM.




Postdoctoral scientist

Degree in Biology (Genetics) in 2008 and PhD in Biology from the Complutense University of Madrid in 2014. In 2010 she joined the Cell Structure Laboratory (CSL) of the National Biotechnology Center where she developed her PhD project. In 2012 she worked at the Plant Pathology Department, University of Kentucky, USA. She is currently a postdoctoral scientist in the CSL.

Present work

Dr. Fernández de Castro uses advanced light and electron microscopy methods to investigate the biogenesis and architecture of viral factories assembled by RNA viruses.


RAQUEL TENORIO VELAraquel tenorio vela

Postdoctoral scientist

Dr. Tenorio obtained her degree in biology from the University of Barcelona in 2000 and her PhD from the Autonomous University of Madrid in 2007. She worked as a Postdoctoral Research Fellow in the International Institute of Infection and Immunity-Medical College Shantou University (UHN Shanghai) in China (2007-2010).  In October 2014 she joined the Risco laboratory as a postdoctoral researcher.

Present works

Her current projects focus on the characterization of structures assembled by RNA viruses in mammalian and arthropod cells.


MOISÉS GARCÍA SERRADILLAMoises garcia serradilla


Moisés has been a predoctoral scientist at the CNB-CSIC, supervised by Dr. Risco. In November 2019, he obtained his PhD in Biology from the Autónoma University of Madrid. As part of his thesis project, Moisés has characterized several antiviral drugs against pathogenic arboviruses.

Present work

Moisés is Associate Professor at the Faculty of Medicine of the Universidad Complutense of Madrid and collaborates with the CSL to discover new antivirals.


PAULA ORTEGA GONZÁLEZPaula ortega gonzalez

Predoctoral scientist

Graduated in biology from the Universidad Autónoma de Madrid (UAM) in 2016 and completed her education with a MSc in Biomolecules and Cellular Dynamics at the UAM. Paula worked with both reoviruses and bunyaviruses during her lab practical classes.

Present work

Paula is now developing her PhD project on the role of lipid transfer proteins in reovirus  infection.




Predoctoral scientist

Alberto graduated in Biochemistry from the Complutense University of Madrid in 2013, and completed his education with an MSc in Molecular Biomedicine at Autónoma University of Madrid. His scientific experience has been related to molecular virology, he has previously worked on structural proteins of Hepatitis C virus and restriction factors of Human Immunodeficiency virus.

Present work

Alberto is currently enrolled on the PhD in Molecular Biosciences Programe (UAM). Through his doctoral thesis project, he tries to identify and characterise the role of lipid transfer proteins during bunyavirus infection.



Lab Manager

Sara obtained the baccalaureate in Health Sciences, a technical degree in Clinical Diagnostic and a degree in Environmental Health from the IES Camilo José Cela, Renacimiento and San Juan de la Cruz schools of Madrid. She attended several courses in computing, biology and pathology and joined the lab in April 2017 with a contract for technicians of the Comunidad de Madrid.

Present work

Sara is presently specializing in virology, biochemistry and microscopy while giving support to different research projects of the CSL.


Master student

Shannon is currently undertaking a Master of Science degree (MSci) in Molecular Biology at the University of Aberdeen, Scotland. She has joined the Cell Structure Laboratory for a summer internship where she is learning antiviral drug and Microscopy techniques. Shannon will begin her year in industry at the Ulsan National Institute of Science and Technology, Korea in September where she will research genetic repair systems (Lem-3/ANLKE-1).